Unveiling the spectrum: A cross-sectional exploration of hirsutism causes in women

  • Rana Tabassum Ansari
  • Uneeba Syed
  • Musarrat Riaz
  • Saima Askari Baqai Institute of Diabetology and Endocrinology, Baqai Medical University
  • Sarwat Anjum
Keywords: Congenital Adrenal Hyperplasia, Hirsutism, Hyperandrogenism, Polycystic ovaries, Ferriman-Gallwey score


Background and Objective: Hirsutism is a common endocrine disorder and its etiology varies from benign and idiopathic disorders to serious malignant diseases. Hirsutism creates negative impact on quality of life and considerable effects on fertility. Our objective was to determine the various causes of hirsutism in women presenting at two endocrine clinics.

Method: This cross-sectional study was conducted at Baqai Institute of Diabetology and Endocrinology, Karachi and at Jinnah hospital, Lahore from August 2020 to December 2021 women between 12-45 years of age with complains of hirsutism were included in the study. Severity of Hirsutism was evaluated using modified Ferriman-Gallwey score (FG). Patients with modified FG score of 8 or more were considered having hirsutism.

Results: The study had 113 patients with a mean age of 15.50+7.29 years with 89% having moderate hirsutism (FG score 16-25). Polycystic ovaries was the most common cause of hirsutism. Common sites for hirsutism included back (83%), arms (74%), buttocks (70%), and upper abdomen (47%). High BMI (p-value <0.01) and high Dehydroepiandrosterone levels were positively associated with the severity of hirsutism (p-value of 0.006).

Conclusion: The various causes of hirsutism identified were polycystic ovaries, followed by idiopathic, thyroid dysfunction, congenital adrenal hyperplasia, and hyperprolactinemia; therefore, all women presenting with hirsutism should be evaluated for potential serious and curable etiologies, before embarking on a treatment plan.

doi: https://doi.org/10.12669/pjms.40.4.8271

How to cite this: Ansari RT, Syed U, Riaz M, Askari S, Anjum S. Unveiling the spectrum: A cross-sectional exploration of hirsutism causes in women. Pak J Med Sci. 2024;40(4):736-740. doi: https://doi.org/10.12669/pjms.40.4.8271

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite
Ansari, R. T., Syed, U., Riaz, M., Askari, S., & Anjum, S. (2024). Unveiling the spectrum: A cross-sectional exploration of hirsutism causes in women. Pakistan Journal of Medical Sciences, 40(4). https://doi.org/10.12669/pjms.40.4.8271
Original Articles