Safety of fasting in diabetic and non-diabetic patients with stable chronic kidney disease during Ramadan

  • Anita Haroon Baqai Medical University
  • Musarrat Riaz baqai medical university
  • Bushra Rabbani Baqai Medical University
  • Ammarah Saeed Fazaia Medical College
Keywords: Ramadan, Fasting, Stable CKD, eGFR

Abstract

Objective: To assess the safety of fasting in diabetic and non-diabetic patients with stable CKD during Ramadan.

Methods: This prospective observational study was conducted at three secondary and tertiary care hospitals of Karachi during the month of Ramadan from 25th March to 7th May 2022. Patients who met the eligibility criteria were assessed pre-Ramadan, and their baseline blood pressure, serum urea, creatinine, electrolytes, uric acid, and estimated glomerular filtration rate (eGFR) were documented and tracked over the course of Ramadan and up to one week post-Ramadan. Deterioration in renal functions (defined as a rise of ≥30% in serum creatinine from the baseline or the decline of ≥25% in eGFR from the baseline) was observed during the month of Ramadan.

Results: A total of 68 patients (34 males and 32 females) with the mean age 58.7±12.16 years were included in the study. Out of 66 patients, 38 were diabetic and 28 were non diabetic. Majority 23(34.8%) were stage-3a and 23(34.8%) were stage-4 followed by stage-3b in 14(21.2%), stage-2 in 3(4.5%) and stage-5 in 3(4.5%) patients respectively. Statistically significant improvement in pre and post Ramadan values of systolic and diastolic blood pressure, serum creatinine and uric acid levels were found in both diabetic and non-diabetic group (P value <0.0001).

Conclusion: Our study shows no worsening of renal functions in both diabetic and non-diabetic patients with stable CKD who intended to fast.

doi: https://doi.org/10.12669/pjms.40.4.7989

How to cite this: Haroon A, Riaz M, Rabbani B, Saeed A. Safety of fasting in diabetic and non-diabetic patients with stable chronic kidney disease during Ramadan. Pak J Med Sci. 2024;40(4):563-567. doi: https://doi.org/10.12669/pjms.40.4.7989

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Anita Haroon, Baqai Medical University

Anita Haroon, MRCP (UK), FCPS (Nephrology), FRCP (UK)

Assistant Professor Department of Nephrology, Baqai Medical University

Karachi, Pakistan.

Musarrat Riaz, baqai medical university

Musarrat Riaz, FCPS (Med), FCPS (Endocrinology)

Associate Professor Department of Medicine, Baqai Medical University

Karachi, Pakistan

Bushra Rabbani, Baqai Medical University

Assistant Professor Department of Medicine, Baqai Medical University

Karachi, Pakistan

Published
2024-02-03
How to Cite
Haroon, A., Riaz, M., Rabbani, B., & Saeed, A. (2024). Safety of fasting in diabetic and non-diabetic patients with stable chronic kidney disease during Ramadan. Pakistan Journal of Medical Sciences, 40(4). https://doi.org/10.12669/pjms.40.4.7989
Section
Original Articles