@article{Kidwai_Nageen_Bashir_Ara_2020, title={HbA1c – A predictor of dyslipidemia in type 2 Diabetes Mellitus}, volume={36}, url={https://pjms.org.pk/index.php/pjms/article/view/2000}, DOI={10.12669/pjms.36.6.2000}, abstractNote={<p><em><strong>Objective:</strong></em> This study was aimed to determine the predictive value of HbA1c in detecting dyslipidemia in patients with Type-2 Diabetes Mellitus.</p> <p><em><strong>Methods:</strong></em> A total of 142 consecutive patients of Type-2 diabetes mellitus were recruited in this study after informed consent. The study was conducted for 6 months from January 2019 – June 2019 in Creek General Hospital, Korangi, Creek, Karachi. Demographic data and detailed history was taken. A complete systemic examination was done for any complications or co-morbids present and related investigations were performed including Fasting lipid profile (CHO, TG’s, HDL, LDL, CHO/HDL), serum HbA1c, Creatinine and ECG. Data is analyzed on SPSS 16 for mean, frequencies and correlations. Pearsons Chi square test is used for analyses of Correlation</p> <p><em><strong>Results:</strong></em> In a total of 142 Type-2 diabetic patients 39(27.5%) were Males and 103(72.5%) were females with a male to female ratio of 1: 2.6. Mean age was 54.9yrs ± 10.7SD. Mean duration of diabetes was 7.37yrs ±5.64 SD years. Mean BMI is 26.8 ± 3.67kg/m2. 27(19.01%) patients had HbA1c ≤ 7% whereas 115(80.9%) had &gt;7%. 81(57.04%) patients had dyslipidemia. HbA1c exhibited direct correlations with BMI, cholesterol, TG’s and LDL and inverse correlation with HDL with significant P value of &lt;.05. TG’s were found significantly higher in females when compared with male patients. In addition, Metabolic syndrome also showed a strong correlation with increasing HbA1c levels especially in female gender (P0.001).</p> <p><em><strong>Conclusion:</strong> </em>The results of our study indicates that HbA1c can be used not only as a useful biomarker of long-term glycaemic control but also a good predictor of lipid profile.</p> <p><strong>doi: https://doi.org/10.12669/pjms.36.6.2000</strong></p> <p><em><strong>How to cite this:</strong></em><br>Kidwai SS, Nageen A, Bashir F, Ara J. HbA1c – A predictor of dyslipidemia in type 2 Diabetes Mellitus. Pak J Med Sci. 2020;36(6):1339-1343. doi: https://doi.org/10.12669/pjms.36.6.2000</p> <p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p&gt;}, number={6}, journal={Pakistan Journal of Medical Sciences}, author={Kidwai, Saera Suhail and Nageen, Ayesha and Bashir, Farhat and Ara, Jamal}, year={2020}, month={Aug.} }