Validation and exploratory factor analysis of Urdu Version of Chronic Liver Disease Questionnaire

Keywords: Cirrhosis, Health Related Quality of Life, CLDQ, Urdu, Exploratory Factor Analysis

Abstract

Objective: To present and validate psychometric properties of Urdu version CLDQ, yet another objective was to do exploratory factorial analysis (EFA) of CLDQ Urdu version.

Methods: This Cross-sectional Analytical Study was conducted at Dr. Ruth K.M. Pfau Civil Hospital Karachi during the period Nov. 15, 2021 to Jan. 30, 2022. CLDQ Urdu questionnaire was self-administered by the patients. The questionnaire consisted of 29 items and responses were recorded on 7-point Likert type scale. Reliability testing was done by Cronbach’s α, test value of >0.7 is taken as reliable. Exploratory factor analysis (EFA) was conducted with principal component analysis with varimax rotation. Adequacies for conduction of EFA depended on Kaiser-Meyer-Olkin (KMO) value of ≥0.5 and Bartlett’s Test of Sphericity (BTS) of ≤0.05. Mean CLDQ Urdu scores were also compared with Child Class using ANOVA and post-hoc analysis was done.

Results: A total of 320 patients were selected after informed consent. All conditions for adequate EFA were met (Cronbach’s α =.949; KMO = .846; BTS ≤.001). Mean CLDQ Urdu score was 156.74 in male and 133.27 in female (p<.001). Child Class-A had best quality of life with score of 186.63 ±6.91 and Child Class-C had the worst with scores of 109.78 ±21.33. EFA resulted in reduction of domains to 4 (Muscular Symptoms, Emotional Symptoms, Abdominal Symptoms & Somnolence) & reduced the number of items from 29 to 11.

Conclusion: Urdu CLDQ version is validated in our settings. EFA resulted in reductions in number of domains and items. CLDQ Urdu showed that quality of life decreases significantly with Child Class.

doi: https://doi.org/10.12669/pjms.39.1.6602

How to cite this: Hussain SM, Zuberi BF, Rasheed T, Ali FS, Majid E. Validation and exploratory factor analysis of Urdu Version of Chronic Liver Disease Questionnaire. Pak J Med Sci. 2023;39(1):---------. doi: https://doi.org/10.12669/pjms.39.1.6602

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Sana Muhammad Hussain, Dow University of Health Sciences, Karachi, Pakistan

Consultant Physiican

Bader Faiyaz Zuberi, Dow University of Health Sciences

Gastroenterologist and Hepatologist
Professor of Medicine
Chairman Department of Medicine
Director Institute of Clinical Sciences
Director Clinical Trials Unit
Dow Medical College
Karachi, Pakistan

Tazeen Rasheed, Dow University of Health Sciences, Karachi, Pakistan

Associate Professor

Faiza Sadaqat Ali, Dow University of Health Sciences, Karachi, Pakistan

Senior Registrar

Erum Majid, Jinnah Postgraduate Medical Centre, Karachi, Pakistan

Associate Professor

Published
2022-11-22
How to Cite
Hussain, S. M., Zuberi, B. F., Rasheed, T., Ali, F. S., & Majid, E. (2022). Validation and exploratory factor analysis of Urdu Version of Chronic Liver Disease Questionnaire. Pakistan Journal of Medical Sciences, 39(1). https://doi.org/10.12669/pjms.39.1.6602

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