Clinical analysis of distribution and drug resistance of pathogenic bacteria in blood culture of Dalian Municipal Central Hospital from 2015 to 2019
Objectives: To analyze the distribution of common pathogenic bacteria and pattern of drug resistance in the blood culture of inpatients.
Methods: This was a descriptive study. Blood culture data of inpatients of Dalian Municipal Central Hospital from January 2017 to December 2020 were collected from microbiology laboratory for retrospective analysis.
Results: A total of 24,786 specimens were submitted for examination from inpatients from 2015 to 2019, and 2131 strains of clinically non-repetitive pathogenic bacteria were identified. There were 1135 G-positive cocci (53.26%), including 248 strains of Staphylococcus hominis (21.85%) and 68 strains of Streptococcus species (5.99%). Other G-positive cocci 8 strains (0.70%). G-positive cocci were most sensitive to datomycin, linezolid and vancomycin. There were 923 G-negative bacilli (43.31%), including 476 strains (51.57%) of Escherichia coli, 244 strains (26.44%) of Klebsiella pneumoniae and 130 strains (14.08%) of Acinetobacter baumannii. G-negative bacilli were most sensitive to amikacin. Most of the blood specimens were obtained from the ICU patients (42.98%) followed by nephrology (8.68%) and respiratory medicine (7.32%).
Conclusion: G-positive bacteria were mainly detected in the positive blood culture samples of inpatients in this hospital. Daptomycin, linezolid and vancomycin were preferred for G-positive cocci, while amikacin was highly sensitive to G-negative bacilli.
How to cite this:
Gao J, Song J. Clinical analysis of distribution and drug resistance of pathogenic bacteria in blood culture of Dalian Municipal Central Hospital from 2015 to 2019. Pak J Med Sci. 2022;38(7):---------. doi: https://doi.org/10.12669/pjms.38.7.5377
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