Clinical analysis of distribution and drug resistance of pathogenic bacteria in blood culture of Dalian Municipal Central Hospital from 2015 to 2019

  • Jinghua Gao Dalian University Affiliated Xinhua Hospital
  • Jing Song
Keywords: Blood culture, Pathogenic bacteria, Drug resistance

Abstract

Objectives: To analyze the distribution of common pathogenic bacteria and pattern of drug resistance in the blood culture of inpatients.

Methods: This was a descriptive study. Blood culture data of inpatients of Dalian Municipal Central Hospital from January 2017 to December 2020 were collected from microbiology laboratory for retrospective analysis.

Results: A total of 24,786 specimens were submitted for examination from inpatients from 2015 to 2019, and 2131 strains of clinically non-repetitive pathogenic bacteria were identified. There were 1135 G-positive cocci (53.26%), including 248 strains of Staphylococcus hominis (21.85%) and 68 strains of Streptococcus species (5.99%). Other G-positive cocci 8 strains (0.70%). G-positive cocci were most sensitive to datomycin, linezolid and vancomycin. There were 923 G-negative bacilli (43.31%), including 476 strains (51.57%) of Escherichia coli, 244 strains (26.44%) of Klebsiella pneumoniae and 130 strains (14.08%) of Acinetobacter baumannii. G-negative bacilli were most sensitive to amikacin. Most of the blood specimens were obtained from the ICU patients (42.98%) followed by nephrology (8.68%) and respiratory medicine (7.32%).

Conclusion: G-positive bacteria were mainly detected in the positive blood culture samples of inpatients in this hospital. Daptomycin, linezolid and vancomycin were preferred for G-positive cocci, while amikacin was highly sensitive to G-negative bacilli.

doi: https://doi.org/10.12669/pjms.38.7.5377

How to cite this:
Gao J, Song J. Clinical analysis of distribution and drug resistance of pathogenic bacteria in blood culture of Dalian Municipal Central Hospital from 2015 to 2019. Pak J Med Sci. 2022;38(7):---------. doi: https://doi.org/10.12669/pjms.38.7.5377

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published
2022-08-02
How to Cite
Gao, J., & Song, J. (2022). Clinical analysis of distribution and drug resistance of pathogenic bacteria in blood culture of Dalian Municipal Central Hospital from 2015 to 2019. Pakistan Journal of Medical Sciences, 38(7). https://doi.org/10.12669/pjms.38.7.5377
Section
Original Articles