Role of free style Libre-Flash Glucose Monitoring: Glycemic control of Type-1 Diabetes

  • Imad Mohamed Taif University
  • Iman M. Talaat
  • Hamed A. Alghamdi
  • Gamal Allam
Keywords: Free style libre-flash glucose monitoring, Glycaemic control, Glycated hemoglobin, Type-1 diabetes

Abstract

Background & Objective: Type-1 diabetics (T1D) usually do not meet guidelines for glycaemic control. This study aimed to determine the benefit of free style libre-flash glucose monitoring system (FSL-FGM) in lowering glycated hemoglobin (HbA1c) in poorly controlled T1D patients.

Methods: This prospective two single arm clinical study included 273 T1D patients, and data collected at one, six and 18 months with concomitant extraction of samples for HbA1c basal and at six and 18 months. The study was conducted in Prince Mansour Military Hospital at Taif, Saudi Arabia from June 2017 to November 2018.

Results: HbA1c % was significantly diminished in patients used FSL-FGM at 6 and 18 months. The median percentage difference in HbA1c at 6 and 18 months versus basal was significantly decreased in those using FSL-FGM. Within diabetics using FSL-FGM, the median difference in HbA1c after 18 months was significantly decreased in patients with HbA1c >10% compared to those with HbA1c <10%. Estimated HbA1c by FSL showed a significant correlation with HbA1C assayed in the blood. The snapshot information showed a highly significant difference in average glucose with low significant difference in hypoglycemia parameters. The FSL-FGM provides significant changes in HbA1c in diabetic patients without observed risk for hypoglycemia.

Conclusions: The dynamic way of blood glucose monitoring using FSL-FGM provides improvement in HbA1c in diabetic patients without observed risk for hypoglycemia.

doi: https://doi.org/10.12669/pjms.37.7.4114

How to cite this:
Mohamed IAA, Talaat IM, Alghamdi HA, Allam G. Role of free style Libre–Flash Glucose Monitoring: Glycemic control of Type-1 Diabetes. Pak J Med Sci. 2021;37(7):1883-1889. doi: https://doi.org/10.12669/pjms.37.7.4114

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published
2021-10-05
How to Cite
Mohamed, I., Talaat, I., Alghamdi, H., & Allam, G. (2021). Role of free style Libre-Flash Glucose Monitoring: Glycemic control of Type-1 Diabetes. Pakistan Journal of Medical Sciences, 37(7). https://doi.org/10.12669/pjms.37.7.4114
Section
Original Articles