Frequency of hyponatremia caused by sodium picosulfate solution when used as a bowel cleansing agent for colonoscopy

  • Tazeen Rasheed DUHS
  • Haris Alvi Dow University of Health Sciences
  • Majid Ahmed Shaikh Dow University of Health Sciences
  • Faiza Sadaqat Ali Dow University of Health Sciences
  • Bader Faiyaz Zuberi Dow University of Health Sciences
  • Wara Subhan Dow University of Health Sciences
Keywords: Colonoscopy, Sodium picosulphate, Hyponatremia, Bowel Preparation

Abstract

Objective: To determine the frequency of hyponatremia in patients taking Sodium Picosulfate Solution (SPS) solution for bowel preparation prior to colonoscopy and to compare serum sodium levels before and after SPS.

Methods: This interventional study was conducted at Dr. Ruth K. M. Pfau, Civil Hospital Karachi between June 2019 to November 2019. Patients undergoing colonoscopy were included in the study. All patients were given SPS. Two samples of blood for electrolytes were taken, one 30 minutes before taking SPS solution and another 30 minutes before colonoscopy. Paired sample t-test was used to determine the difference between serum sodium level before taking the colonoscopy solution and serum sodium level before colonoscopy.

Results: Fifty- four patients fulfilling inclusion criteria were included. Out of the 54 patients 28 (51.9%) were males and 26 (48.1%) were females. Mean sodium levels before taking colonoscopy solution was 139.7±3.5 mEq/L and mean sodium level before colonoscopy was 138.9±3.8 mEq/L. The difference between serum sodium level before taking SPS colonoscopy solution and before colonoscopy was found to be statistically insignificant (t (53) = 1.308; p = 0.196).

Conclusion: No serious adverse effects were reported in any of our patients. There was no significant difference in the serum sodium level of patients undergoing colonoscopy before taking SPS bowel preparation solution and serum sodium level before colonoscopy.

doi: https://doi.org/10.12669/pjms.36.7.2376

How to cite this:
Rasheed T, Alvi H, Shaikh MA, Ali FS, Zuberi BF, Subhan W. Frequency of hyponatremia caused by sodium picosulfate solution when used as a bowel cleansing agent for colonoscopy. Pak J Med Sci. 2020;36(7):1651-1654.
doi: https://doi.org/10.12669/pjms.36.7.2376

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Haris Alvi, Dow University of Health Sciences

Professor

 

Majid Ahmed Shaikh, Dow University of Health Sciences

Assistant Professor

Faiza Sadaqat Ali, Dow University of Health Sciences

Senior Registrar

Bader Faiyaz Zuberi, Dow University of Health Sciences

Professor

Wara Subhan, Dow University of Health Sciences

Postgraduate trainee

Published
2020-10-19
How to Cite
Rasheed, T., Alvi, H., Shaikh, M., Ali, F., Zuberi, B., & Subhan, W. (2020). Frequency of hyponatremia caused by sodium picosulfate solution when used as a bowel cleansing agent for colonoscopy. Pakistan Journal of Medical Sciences, 36(7). https://doi.org/10.12669/pjms.36.7.2376
Section
Original Articles

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