Quality of Life in relation to Vitamin-D levels in asymptomatic young health care professionals in a tertiary care hospital: Quality of Life and Vitamin-D (QoLD) study

Abstract

Objectives: We have assessed the Vitamin-D status and its association with health-related quality of life in asymptomatic young health care professionals in a tertiary care hospital in Pakistan.

Methods: This cross-sectional study was conducted in a tertiary care hospital in Pakistan. Three hundred and nineteen asymptomatic healthy health care professionals (HCPs) aged 20-40 years of age were enrolled in July 2023 using non-probability convenient sampling method The Medical Outcomes Study 36-Item Short Form Health Survey measured health related quality of life (HRQoL). ANOVA compared continuous variables, while Chi-square tested categorical variables. Results were considered statistically significant with a p value < 0.05 in the two-sided analysis. 

Results: From July 1st to July 31st, 2023, 319 individuals were recruited, with a mean age of 28·2 ± 4·96 years, with 230 (72·1%) males and 89 (27·9%) females. The mean serum 25-hydroxyVitamin-D concentration was 24·9 ± 9·55 ng/ml with 82·1% being either deficient or insufficient. The mean physical component score (PCS), mental component score (MCS) and total SF 36 score were 81·2 ± 11·4, 77·9 ± 12·9 and 79·6 ± 11·1 respectively. There was no association between Vitamin-D levels and the SF 36 score (p value > 0·05).

Conclusion: Most asymptomatic young HCPs were Vitamin-D insufficient, whilst 95% had a mean SF 36 score >50. However, there was no relationship between Vitamin-D status and the quality of life.