Narrowed pulse pressure as a predictor of active hemorrhage in hemodynamically stable blunt trauma: Insights from an Asian cohort

Authors

  • Juan Peng The Second Affiliated Hospital, Department of Emergency medicine, Hengyang Medical School, University of South China
  • Dandan Jiang The Second Affiliated Hospital, Department of Emergency medicine, Hengyang Medical School, University of South China
  • Shan Liu The Second Affiliated Hospital, Department of Emergency medicine, Hengyang Medical School, University of South China
  • Chanjuan Yang The Second Affiliated Hospital, Department of Emergency medicine, Hengyang Medical School, University of South China

DOI:

https://doi.org/10.12669/pjms.41.12.11505

Keywords:

Traumatic hemorrhage, blunt trauma, pulse pressure, propensity score matching

Abstract

Objective: This study aimed to assess the predictive value of pulse pressure (PP) for identifying the critical administration threshold (CAT) in hemodynamically stable patients with active bleeding following blunt trauma.

Methods: This retrospective study included hemodynamically stable blunt trauma patients treated from 2021 to 2022 in our hospital. Patients were grouped by CAT+ or CAT- status. Propensity score matching (PSM) was used to balance baseline characteristics. Logistic regression analyses evaluated the predictive value of PP, while receiver operating characteristic curve (ROC) analysis was performed to determine optimal thresholds in elderly patients (age >60 years).

Results: Of 456 patients, 65 (14.3%) were classified as CAT+. PP ≤40 mmHg was an independent predictor of CAT+ before PSM (OR = 5.931; 95% CI, 2.648–13.284; P < 0.001) and after PSM (adjusted OR = 4.579; 95% CI, 1.193–10.958; P = 0.016). In elderly patients, the optimal PP threshold for CAT+ was ≤41.5 mmHg, with an area under the curve (AUC) of 0.822 (95% CI, 0.724–0.921).

Conclusion: PP is a reliable predictor of critical hemorrhage in hemodynamically stable blunt trauma patients and elderly subgroups, supporting its use in trauma care.

Author Biographies

Juan Peng, The Second Affiliated Hospital, Department of Emergency medicine, Hengyang Medical School, University of South China

MB, Registered Nurse, The Second Affiliated Hospital, Department of Emergency Medicine

Dandan Jiang, The Second Affiliated Hospital, Department of Emergency medicine, Hengyang Medical School, University of South China

M.Med., Nursing Officer,Department of Emergency Medicine

Shan Liu, The Second Affiliated Hospital, Department of Emergency medicine, Hengyang Medical School, University of South China

 M.Med., Attending Physician, Department of Emergency Medicine

Chanjuan Yang, The Second Affiliated Hospital, Department of Emergency medicine, Hengyang Medical School, University of South China

M.Med., Attending Physician,  Department of Emergency Medicine

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Published

2025-11-25

How to Cite

Peng, J., Jiang, D., Liu, S., & Yang, C. (2025). Narrowed pulse pressure as a predictor of active hemorrhage in hemodynamically stable blunt trauma: Insights from an Asian cohort. Pakistan Journal of Medical Sciences, 41(12), 3533–3539. https://doi.org/10.12669/pjms.41.12.11505

Issue

Section

Original Articles