@article{Awan_Jan_Rehman_Ayaz_2020, title={The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients}, volume={36}, url={https://pjms.org.pk/index.php/pjms/article/view/3266}, DOI={10.12669/pjms.36.7.3266}, abstractNote={<p><em><strong>Background and Objectives:</strong></em> Patients with low ejection fraction undergoing isolated CABG surgery are at a higher risk for postoperative complications and mortality. This study was conducted to evaluate the impact of ejection fraction on the outcome of isolated Coronary Artery Bypass Grafting (CABG).</p> <p><em><strong>Methods:</strong> </em>Between July, 2017 to May, 2019 total 1214 patients underwent isolated CABG. Patients were divided into three groups based on their pre-operative Ejection Fraction (EF). Group-I included 625 patients with EF &gt;50% [Normal EF], Group-II included 484 patients with EF 35-50% [Mild to Moderately Reduced EF], and Group 3 included 105 patients with EF &lt;35% [Severely Reduced EF].</p> <p><em><strong>Results:</strong></em> The mean age of Group-I was 57.58 ± 9.206, Group-II was 58.38±9.124 and Group-III was 58.81± 8.663.The male gender was the predominant gender in all three groups: 194(41.1%) in Group-I, 201(52.6%) in Gp2, 52 (61.9%) in Group-III. 231(36.9) patients in Group-I, 234(48.3)in Group-II and 59(56.2) in Group-III had raised creatinine pre operatively. 5(0.8%) patients in Group-I, 2(0.4%) in Group-II and 3(2.9%) in Group-III had history of CVA. Hypertension was present in approximately 60% of all our patients. In the per-operative period 20(3.2%) patients in Group-I required an IABP as compared to 73(15.1%) in Group-II and 41(39.0%) in Group-III. The mean post-operative mortality in Group-I was 19 (3%), Group-II was 24(5.0%) and low EF group was 9(8.6%).</p> <p><em><strong>Conclusions:</strong></em> The results clearly indicate that worsening pre-operative ejection fraction is associated with a higher mortality post-operatively in patients undergoing isolated CABG. In addition, use of IABP increases as pre-operative LVEF decreases.</p> <p><em><strong>Definitions:</strong></em> *PERFUSION TIME: total time on CPB machine. *CROSS CLAMP TIME: Total time that ascending aorta was CROSS clamped. *STROKE: Defined as presence of neurological deficit, findings on CT scan and confirmed by a Neurology consultant. *RE-OP: Re-operation during index admission.</p> <p><strong>doi: https://doi.org/10.12669/pjms.36.7.3266</strong></p> <p><em><strong>How to cite this:</strong></em><br>Awan NI, Jan A, Mujeeb-Ur-Rehman, Ayaz N. The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients. Pak J Med Sci. 2020;36(7):1454-1459. doi: https://doi.org/10.12669/pjms.36.7.3266</p> <p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p&gt;}, number={7}, journal={Pakistan Journal of Medical Sciences}, author={Awan, Nabil Iftikhar and Jan, Azam and Rehman, Mujeeb Ur and Ayaz, Narmeen}, year={2020}, month={Oct.} }