@article{Cirik_Yenibertiz_2020, title={What are the prognostic factors affecting 30-day mortality in geriatric patients with respiratory failure in the Intensive Care Unit?}, volume={37}, url={https://pjms.org.pk/index.php/pjms/article/view/3189}, DOI={10.12669/pjms.37.1.3189}, abstractNote={<p><em><strong>Objective:</strong></em> We aimed to investigate the prognostic factors related to 30 day mortality of elderly patients with respiratory failure in the intensive care unit (ICU).</p> <p><em><strong>Methods:</strong></em> We performed a single centre, retrospective study and analyzed the main variables and outcomes of 238 geriatric patients admitted to an ICU with ARF between December 2017- January 2019 in Chest Disease Hospital, were included and classified as survivors and nonsurvivors. Main characteristics, laboratory datas, severity and nutrition scores were evaluated and logistic regression analysis were used.</p> <p><em><strong>Results:</strong></em> The nonsurvivor group included 110 cases (40% female,) with a median age of 79, had higher scores in the followings; Acute Physiology Chronic Health Evaluation II score (APACHE-II) (p &lt; 0.001), Charlson Comorbidity Index (CCI) (p &lt; 0.001), Sequential Organ Failure Assessment score (p &lt; 0.001). The inotropic support requirement was also higher in the nonsurvivor group (48,2%). As a comorbidity, malignancy and Type-I respiratory failure were higher in the nonsurvivor group (p=0.03, p &lt; 0.001). The overall 30-day mortality was 46%. Blood urea nitrogen, procalsitonin, C-reactive protein and creatinine levels were higher in the nonsurvivor group (p &lt; 0.001). However, albumin (p &lt; 0.001), BMI (p=0.03) and longer hospital stay (p &lt; 0.001) were higher in the survivor group. Inotropic support, APACHE-II score and CCI were independently related to increased mortality risk, whereas albumin was associated with decreased mortality risk.</p> <p><em><strong>Conclusion:</strong></em> High APACHE II score, low CCI, low albumin levels and the requirement for inotropic support were found to be independently risk factors of 30-day mortality in the geriatric patients with respiratory failure in ICU.</p> <p><strong>doi: https://doi.org/10.12669/pjms.37.1.3189</strong></p> <p><em><strong>How to cite this:</strong></em><br>Cirik MO, Yenibertiz D. What are the prognostic factors affecting 30-day mortality in geriatric patients with respiratory failure in the Intensive Care Unit? Pak J Med Sci. 2021;37(1):15-20. doi: https://doi.org/10.12669/pjms.37.1.3189</p> <p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p&gt;}, number={1}, journal={Pakistan Journal of Medical Sciences}, author={Cirik, Mustafa Özgür and Yenibertiz, Derya}, year={2020}, month={Dec.} }