Polycystic Ovarian Syndrome: Correlation between clinical hyperandrogenism, anthropometric, metabolic and endocrine parameters

Polycystic Ovarian Syndrome

  • Ayesha Khan Bahria university Medical and Dental College
  • Nasim Karim
  • Jahan Ara Ainuddin
  • Muhammad Faisal Faheem
Keywords: PCOS, Hirsutism, F-G score, Correlation, Anthropometric parameters, Metabolic parameters, Endocrine parameters

Abstract

Objective: To evaluate the correlation between clinical hyperandrogenism-hirsutism assessed by modified Ferriman-Gallwey (F-G) score, anthropometric, metabolic and endocrine parameters among PCOS infertile women.

Methods: This observational study after approval of FRC & ERC of BUMDC was conducted from September 2018-March 2019. It included seventy women aged 20-40 years who presented in infertility clinic of a local Hospital in Karachi. After written informed consent participants were enrolled as per the inclusion criteria of the study and evaluated for cyclical pattern (oligomenorrhoea, amenorrhoea, polymenorrhea), physical (weight, height, BMI), anthropometric, (waist circumference, hip circumference, waist to hip ratio, hirsutism), metabolic (carbohydrate, lipid & protein) and endocrine parameters (serum FSH, LH, LH/FSH ratio, serum testosterone, prolactin and progesterone level). Hirsutism was assessed by visual method through modified F-G score and Pearson correlation was determined between hirsutism and other study parameters.

Results: A positive Pearson correlation is found between hirsutism and body weight, BMI, waist and hip circumference, waist to hip ratio (WHR), very low density lipoprotein, cholesterol, triglycerides and testosterone levels.

Conclusion: Hirsutism has correlation with anthropometric, metabolic and hyperandrgenic disorders in PCOS infertile women as assessed by modified F-G score.

doi: https://doi.org/10.12669/pjms.35.5.742

How to cite this:
Khan A, Karim N, Ainuddin JA, Fahim MF. Polycystic Ovarian Syndrome: Correlation between clinical hyperandrogenism, anthropometric, metabolic and endocrine parameters. Pak J Med Sci. 2019;35(5):1227-1232.
doi: https://doi.org/10.12669/pjms.35.5.742

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Nasim Karim

Professor & HOD Pharmacology

Jahan Ara Ainuddin

Professor & HOD Obstetrics & Gynecology

Muhammad Faisal Faheem

Consultant Statistician

Department of Bahria University College of Physical Therapy

Published
2019-08-21
Section
Original Articles