Three-dimensional transvaginal ultrasonography in the evaluation of diminished ovarian reserve and premature ovarian failure

  • Qian Chen
  • Lu Sun
  • Jian Huang
  • Fan Huang
  • Shuang Guo
  • Yiqing Chai Tianjin Central Hospital of Gynecology Obstetric
Keywords: Three-dimensional transvaginal ultrasonography, Diminished ovarian reserve, Premature ovarian failure

Abstract

Objective: To explore the applicability of three-dimensional transvaginal ultrasonography (3D-TVS) in the evaluation of diminished ovarian reserve (DOR) and premature ovarian failure (POF).

Methods: One hundred and twenty female patients, who received 3D-TVS in our hospital from January 2020 to March 2022, were included in the study. Based on sex hormone examination, 25 cases were DOR (DOR-group), 32 cases were POF (POF-group) and 63 cases had normal ovarian function (Normal-group). The 3D-TVS quantitative examination results of the three groups of patients were analyzed and compared.

Results: There was no significant difference between the DOR-group and POF-group regarding antral follicles count (AFC), ovarian volume (OV), vascularization index (VI), vascularization flow index (VFI) and flow index (FI) of left and right ovaries (p>0.05). Compared with the Normal-group, the 3D-TVS examination indexes of the DOR-group and POF-group were significantly lower, and the 3D-TVS examination results of the POF-group were significantly lower than those of the DOR-group (p<0.05). Using sex hormone examination as the gold standard, the diagnostic specificity of 3D-TVS for DOR was 80%, and the sensitivity and accuracy were 90% and 88% respectively; The diagnostic specificity of POF was 87.5%, the sensitivity and accuracy were 95.8% and 93.8% respectively.

Conclusion: 3D-TVS can provide scientific guidance for the clinical diagnosis and evaluation of DOR and POF.

doi: https://doi.org/10.12669/pjms.39.3.7372

How to cite this: Chen Q, Sun L, Huang J, Huang F, Guo S, Chai Y. Three-imensional transvaginal ultrasonography in the evaluation of diminished ovarian reserve and premature ovarian failure. Pak J Med Sci. 2023;39(3):747-751. doi: https://doi.org/10.12669/pjms.39.3.7372

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published
2023-03-27
How to Cite
Chen, Q., Sun, L., Huang, J., Huang, F., Guo, S., & Chai, Y. (2023). Three-dimensional transvaginal ultrasonography in the evaluation of diminished ovarian reserve and premature ovarian failure. Pakistan Journal of Medical Sciences, 39(3). https://doi.org/10.12669/pjms.39.3.7372
Section
Original Articles