Pathological discrepancy between colposcopic directed cervical biopsy and conisation results: A five years experience of a single center in Turkey

Cone Biopsy Results of a Single Center in Turkey

  • Hüseyin Aydoğmuş İzmir Katip Çelebi University Ataturk Research and Training Hospital
  • Serhat Sen Department of Gynecology and Obstetrics, İzmir Katip Çelebi University Atatürk Research and Training Hospital
  • Serpil Aydogmus İzmir Katip Çelebi University Scholl of Medicine, Department of Gynecology and Obstetrics
Keywords: Abnormal smear, Colposcopy, Conisation

Abstract

Objective: To analyze the clinical outcomes and treatment strategies of patients who underwent conisation in a tertiary hospital clinic

Methods: The study was designed as a retrospective cohort study. Retrospective data’s of 176 patients who underwent conisation due to detection of dysplasia via colposcopic biopsy or cytology-histology discrepancy between 2012 and 2017 were collected. Colposcopy guided biopsies were performed according to HPV positivity and/or abnormal smear results in Izmir Katip Celebi University Ataturk Research and Training Hospital.

Results: Indications for colposcopic biopsies were HPV positivity in 51 patients (29.1%), abnormal smear results in 125 patients (70.9 %). Distribution of abnormal smear results were ASCUS, ASC-H, LSIL, HSIL in 6 (4.8 %), 21 (16.8 %), 24 (19.2%), 74 (59.2%) patients respectively. According to biopsy results, 8 patients (4.4 %) showed no dysplasia where two (1.1%) and 162 (91.5 %) patients were with LSIL and HSIL respectively. Only two were diagnosed with in situ carcinoma. Among 162 patients with HSIL in colposcopic biopsy, 45 showed no dysplasia where four were diagnosed with invasive carcinoma.

Conclusions: To detect high grade cervical lesions colposcopy guided biopsy is gold standard. Although cone biopsy should be performed related to severity of dysplasia in order to sustain the diagnosis and treatment. Contradictory results between colposcopic and cone biopsies should be considered during decision-making process.

doi: https://doi.org/10.12669/pjms.35.6.408

How to cite this:
Aydogmus H, Sen S, Aydogmus S. Pathological discrepancy between colposcopic directed cervical biopsy and conisation results: A five years experience of a single center in Turkey. Pak J Med Sci. 2019;35(6):1627-1630.
doi: https://doi.org/10.12669/pjms.35.6.408

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published
2019-10-08
Section
Original Articles