Association amid the comorbidity of Diabetes Mellitus in patients of Active Tuberculosis in Pakistan: A matched case control study

  • Nadia Khalid Bahria University Medical & Dental College
  • Farah Ahmad, Dr. College of Physicians & Surgeons, Karachi
  • Farhan Muhammad Qureshi, Dr. Karachi Institute of Medical Sciences (KIMS), Malir Cantt, karachi
Keywords: Association, Co-morbidity, Diabetes mellitus, Tuberculosis, Tuberculous infection

Abstract

Objectives: This study aims to test the association between diabetes and tuberculosis.

Methods: It is a matched case control study conducted in tertiary care hospitals in 2019-2020. Cases and controls were 144 each, selected on the basis of an odds ratio of 2 at 95% confidence interval with a significance level of 5%. Cases of pulmonary tuberculosis were selected through consecutive sampling technique, either visiting OPD or admitted in hospital. Controls were taken from the general population and frequency matching was done based on age, gender and socioeconomic status. Data was collected through structured questionnaire after taking written consent. Data was analyzed on SPSS version 23. Binary Logistic regression model was applied for finding association between the risk factors and the disease. P value <0.05 was considered statistically significant.

Results: Out of all cases and controls, 45% and 20% were diabetics respectively. The association between the risk factors and tuberculosis was estimated by univariate analysis, positive association was found between diabetes and tuberculosis (OR= 3.32), a high frequency of diabetes in cases as compared to controls were observed with a highly significant p- value (<0.001).

Conclusions: This study provides evidence for a strong positive association between tuberculosis and diabetes.

doi: https://doi.org/10.12669/pjms.37.3.3274

How to cite this:
Khalid N, Ahmad F, Qureshi FM. Association amid the comorbidity of Diabetes Mellitus in patients of Active Tuberculosis in Pakistan: A matched case control study. Pak J Med Sci. 2021;37(3):816-820. doi: https://doi.org/10.12669/pjms.37.3.3274

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Farah Ahmad, Dr., College of Physicians & Surgeons, Karachi

Associate Director

Health Care System Management (HCSM)

College of Physicians & Surgeons, Karachi

Farhan Muhammad Qureshi, Dr., Karachi Institute of Medical Sciences (KIMS), Malir Cantt, karachi

Assistant Professor

Department of Community Health Sciences

Karachi Institute of Medical Sciences (KIMS) 

National University of Medical Sciences (NUMS)

 

Published
2021-03-26
How to Cite
Khalid, N., Ahmad, F., & Qureshi, F. (2021). Association amid the comorbidity of Diabetes Mellitus in patients of Active Tuberculosis in Pakistan: A matched case control study. Pakistan Journal of Medical Sciences, 37(3). https://doi.org/10.12669/pjms.37.3.3274
Section
Original Articles

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