Common Cancers in Karachi, Pakistan: 2010-2019 Cancer Data from the Dow Cancer Registry

  • Muhammad Asif Qureshi Dow University of Health Sciences
  • Saeed Khan Dow University of Health Sciences Karachi
  • Shaheen Sharafat Dow University of Health Sciences Karachi
  • Mohammed Saeed Quraishy Dow University of Health Sciences Karachi
Keywords: cancer registry, karachi, pakistan, cancer patterns

Abstract

Objectives: To present 2010-2019 cancer data from the Dow Cancer Registry representing all districts of Karachi (~17.4 million).

Methods: The study was conducted at the Dow University of Health Sciences. After ethical approval, the Dow Cancer Registry was established at the largest government-run diagnostic and reference center of Karachi (Dow Labs). All cancers registered during 2010-2019 were analyzed. Patients >18years of age were labeled as adults while those with ages ≤18years were classified as children/young adults.

Results: During 2010-2019, a total of 22,858 cancers were registered. Of these, 9,112(39.9%) cancers were diagnosed in males while 13,746(60.1%) in females. Incidence rates for all cancers (all ages) were 108/1,00,000 for males and 188.6/1,00,000 for females. In adult males, cancer of lip and oral cavity was the most frequently diagnosed cancer (33.6%), followed by non-melanoma –skin-cancer (NMSC) (7.2%), oesophagus (6.8%), colorectum (6.7%) and stomach (4.9%). In adult females, breast cancer was the most frequently recorded malignancy (53.2%), followed by cancers of lip and oral cavity (10.4%), oesophagus (5.3%), colorectum (3.3%) and NMSC (3%). In children, most common malignancy was that of brain and nervous system (15.3%), followed by Hodgkin’s lymphoma (14.2%), colorectum (8.1%), endocrine-&-related organs (8%) and non-Hodgkin’s lymphoma (7.8%)

Conclusion: Cancers of lip and oral cavity and breast cancer were the most common malignancies in males and females respectively. In paediatric group, cancers of brain and nervous system were most common. Alarmingly, Karachi males have highest ASR of cancers of lip and oral cavity compared to any other city of Pakistan.

doi: https://doi.org/10.12669/pjms.36.7.3056

How to cite this:
Qureshi MA, Khan S, Sharafat S, Quraishy MS. Common Cancers in Karachi, Pakistan: 2010-2019 Cancer Data from the Dow Cancer Registry. Pak J Med Sci. 2020;36(7):1572-1578. doi: https://doi.org/10.12669/pjms.36.7.3056

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published
2020-10-19
How to Cite
Qureshi, M. A., Khan, S., Sharafat, S., & Quraishy, M. S. (2020). Common Cancers in Karachi, Pakistan: 2010-2019 Cancer Data from the Dow Cancer Registry. Pakistan Journal of Medical Sciences, 36(7). https://doi.org/10.12669/pjms.36.7.3056
Section
Original Articles