Identification of risk factors for human immunodeficiency virus-1 infection in Khyber Pakhtunkhwa population: A case control study

Risk factors for HIV-1 infection in KP population

  • Jamila Haider Shaheed Benazir Bhutto Women University Peshawar
  • Ghosia Lutfullah University of Peshawar
  • Irshad ur Rehman University of Peshawar
  • Irfan Khattak Abdul Wali Khan University, Mardan.
Keywords: Risk Factors, Human Immunodeficiency Virus-1 (HIV), Injection drug users (IDUs), Blood transfusion, tattooing, Khyber Pakhtunkhwa (KP)

Abstract

Objectives: The present study aims to identify the risk factors for Human Immunodeficiency Virus-1(HIV-1) infection in Khyber Pakhtunkhwa (KP) population by comparing HIV-antibody positive cases with HIV-antibody-negative controls.

Methods: The study was designed at the Family Care Centre (FCC), Hayatabad Medical Centre (HMC) Peshawar from February 2015 to December 2016. A total of 280 individuals were selected randomly for the study as cases and control. Data was collected on a structured questionnaire with informed oral consent. The collected data was analysed statistically using SPSS version 20.

Results: Out of 280 individuals, 56% were males, 44% were females, and 53.21% belonged to the urban areas. The literacy rate was 48.6%, and 75.4% were married. The statistical analysis of risk factors revealed the following factors as of significance value (p < 0.05). Family history of HIV (OR = 9.46), spouse status of HIV (OR=22.22), injection drug users (IDUs), migrants (OR=2.234), use of therapeutic injections (OR= 2.791), employment (OR=2.545), male gender (OR=2.35), tattooing (OR=7.667) and history of blood transfusion (OR= 2.69).

Conclusion: The present study revealed spouse status of HIV, tattooing, migrants, IDUs, use of therapeutic injections, history of blood transfusion, male gender and employment as significant risk factors for HIV infection in the population of KP.

doi: https://doi.org/10.12669/pjms.35.5.258

How to cite this:
Haider J, Lutfullah G, Irshad ur Rehman, Khattak I. Identification of risk factors for human immunodeficiency virus-1 infection in Khyber Pakhtunkhwa population: A case control study. Pak J Med Sci. 2019;35(5):1258-1263.
doi: https://doi.org/10.12669/pjms.35.5.258

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Ghosia Lutfullah, University of Peshawar

Prof. Dr.Ghosia Lutfullah, M.Phil, PhD, Ex. Director, Centre of Biotechnology & Microbiology, University of Peshawar

Irshad ur Rehman, University of Peshawar

Irshad ur Rehman,MPhil, PhD, Assistant Professor, Centre of Biotechnology & Microbiology, University of Peshawar.

Irfan Khattak, Abdul Wali Khan University, Mardan.

Irfan Khattak, DVM, PhD, Assistant Professor, College of Veterinary Sciences & Animal Husbandry, Abdul Wali Khan University, Mardan.

Published
2019-08-21
Section
Original Articles