Association of lamina cribrosa morphometry with retinal nerve fiber layer loss and visual field defects in primary open angle glaucoma

Visual field defects in primary open angle glaucoma

  • Ayesha Saba Naz Bahria University Medical and Dental College, Karachi Pakistan
  • Aisha Qamar
  • Sama Ul Haque
  • Yawar Zaman
  • Faisal Faheem
Keywords: Lamina cribrosa thickness, Lamina cribrosa depth, Visual field defects, Primary open angle glaucoma, SDOCT

Abstract

Objectives: To calculate the anterior lamina cribrosa depth (ALCD) and lamina cribrosa thickness (LCT) in primary open angle glaucoma (POAG) patients and controls and to correlate lamina cribrosa (LC) parameters to retinal nerve fiber layer thickness (RNFLT) and visual field (VF) defects.

Methods: The study was conducted from November 2018 to March 2019. A total of 60 correspondents (30 cases and 30 controls) were assessed for general ophthalmological investigations including intraocular pressure (IOP), axial length AXL, ophthalmoscopy, visual field (VF) testing and spectral domain ocular computed tomography (SDOCT).

Results: The mean age of subjects was 62 years (Cases 67.30±1.2, controls 57.32±1.1) with more male participants. Intraocular pressure [IOP (19.85 ±1.4)], AXL (22.85 ± 1.6), VF defects (8.30 ± 4.5), RNFLT (72.58 ± 13.2) and LCT (162.51 ± 64.62) were statistically significant in POAG patients as compared to the controls.

Conclusion: A thinner LC in POAG correlated significantly with the RNFLT and VF defects. LC anatomical parameters can be estimated with precision using SDOCT with enhanced depth imaging (EDI).

doi: https://doi.org/10.12669/pjms.36.3.1553

How to cite this:
Naz AS, Qamar A, Sama-Ul-Haque, Zaman Y, Faheem F. Association of lamina cribrosa morphometry with retinal nerve fiber layer loss and visual field defects in primary open angle glaucoma. Pak J Med Sci. 2020;36(3):521-525.
doi: https://doi.org/10.12669/pjms.36.3.1553

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published
2020-03-04
How to Cite
Naz, A., Qamar, A., Haque, S. U., Zaman, Y., & Faheem, F. (2020). Association of lamina cribrosa morphometry with retinal nerve fiber layer loss and visual field defects in primary open angle glaucoma. Pakistan Journal of Medical Sciences, 36(3). https://doi.org/10.12669/pjms.36.3.1553
Section
Original Articles